TIROPRAMIDE

Tiropramide is an antispasmodic agent that relaxes smooth muscle by reducing intracellular calcium. It is used for abdominal pain and GI spasms. Side effects include dry mouth, dizziness, nausea, and rare allergic reactions.

SKU: 11a57ffb0158 Category: Tag:

Product Description


Mechanism of Action

TIROPRAMIDE (ID 27687) exerts multi‑axis biochemical modulation involving enzymatic‑cascade interference, receptor‑mediated signalling adjustment, oxidative‑stress balancing, mitochondrial‑respiratory modulation, ion‑channel behaviour influence, cytoskeletal‑architecture modification and transcription‑factor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membrane‑anchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP₃/DAG turnover, cAMP regulation, ATP flux and cellular redox‑state stability.

Benefits & Applications

  • Receptor–ligand interaction and docking studies
  • Kinase/catalytic pathway profiling
  • Mitochondrial ATP/ROS functional modelling
  • Multi‑omics integration research
  • Cytoskeletal and membrane‑dynamics analysis
  • Apoptosis, autophagy and survival‑pathway investigations
  • SAR/QSAR modelling and molecular optimisation

Risks & Side Effects

  • ROS accumulation and oxidative‑stress imbalance
  • Mitochondrial overload or ETC suppression
  • Ion‑channel destabilisation (Ca²⁺/Na⁺/K⁺)
  • Cytoskeletal disruption and membrane integrity loss
  • Dose‑dependent cytotoxicity
  • Inflammatory cascade activation

Datasheet


Molecular Formula

C28H41N3O3

Molecular Weight

467.6 g/mol

CAS Number

55837-29-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Tiropramide; 55837-29-1; Tiropramida; Tiropramidum; R7S0904CN2

IUPAC/Chemical Name

N-[3-[4-[2-(diethylamino)ethoxy]phenyl]-1-(dipropylamino)-1-oxopropan-2-yl]benzamide

InChl Key

FDBWMYOFXWMGEY-UHFFFAOYSA-N

InChl Code

InChI=1S/C28H41N3O3/c1-5-18-31(19-6-2)28(33)26(29-27(32)24-12-10-9-11-13-24)22-23-14-16-25(17-15-23)34-21-20-30(7-3)8-4/h9-17,26H,5-8,18-22H2,1-4H3,(H,29,32)

References

https://pubchem.ncbi.nlm.nih.gov/compound/42262;

3D Conformer.

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