TIAPRIDE

Tiapride is a dopamine D2 antagonist used for agitation, dyskinesia, and alcohol withdrawal symptoms. Side effects include sedation, hypotension, hyperprolactinemia, and QT prolongation. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 23b92994086e Category: Tag:

Product Description


Mechanism of Action

TIAPRIDE exerts multiaxis biochemical modulation involving enzymaticcascade interference, receptormediated signalling adjustment, oxidativestress balancing, mitochondrialrespiratory modulation, ionchannel behaviour influence, cytoskeletalarchitecture modification and transcriptionfactor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membraneanchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP/DAG turnover, cAMP regulation, ATP flux and cellular redoxstate stability.

Benefits & Applications

  • Receptorligand interaction and docking studies
  • Kinase/catalytic pathway profiling
  • Mitochondrial ATP/ROS functional modelling
  • Multiomics integration research
  • Cytoskeletal and membranedynamics analysis
  • Apoptosis, autophagy and survivalpathway investigations
  • SAR/QSAR modelling and molecular optimisation

Risks & Side Effects

  • ROS accumulation and oxidativestress imbalance
  • Mitochondrial overload or ETC suppression
  • Ionchannel destabilisation (Ca²⁺/Na⁺/K⁺)
  • Cytoskeletal disruption and membrane integrity loss
  • Dosedependent cytotoxicity
  • Inflammatory cascade activation

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H24N2O4S

Molecular Weight

328.4 g/mol

CAS Number

51012-32-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

tiapride; 51012-32-9; Thiapride; Tiaprida; Tiapridum

IUPAC/Chemical Name

N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide

InChl Key

JTVPZMFULRWINT-UHFFFAOYSA-N

InChl Code

InChI=1S/C15H24N2O4S/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18)

References

https://pubchem.ncbi.nlm.nih.gov/compound/5467;

3D Conformer.

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