THYMOPENTIN

Thymopentin is a synthetic thymic peptide that enhances T‑cell maturation and immune modulation. It is studied for immunodeficiency and autoimmune disorders. Side effects include injection‑site reactions, flu‑like symptoms, fatigue, and rare hypersensitivity responses.

SKU: 2e944e891283 Category: Tag:

Product Description


Mechanism of Action

THYMOPENTIN (ID 27655) exerts multi‑axis biochemical modulation involving enzymatic‑cascade interference, receptor‑mediated signalling adjustment, oxidative‑stress balancing, mitochondrial‑respiratory modulation, ion‑channel behaviour influence, cytoskeletal‑architecture modification and transcription‑factor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membrane‑anchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP₃/DAG turnover, cAMP regulation, ATP flux and cellular redox‑state stability.

Benefits & Applications

  • Receptor–ligand interaction and docking studies
  • Kinase/catalytic pathway profiling
  • Mitochondrial ATP/ROS functional modelling
  • Multi‑omics integration research
  • Cytoskeletal and membrane‑dynamics analysis
  • Apoptosis, autophagy and survival‑pathway investigations
  • SAR/QSAR modelling and molecular optimisation

Risks & Side Effects

  • ROS accumulation and oxidative‑stress imbalance
  • Mitochondrial overload or ETC suppression
  • Ion‑channel destabilisation (Ca²⁺/Na⁺/K⁺)
  • Cytoskeletal disruption and membrane integrity loss
  • Dose‑dependent cytotoxicity
  • Inflammatory cascade activation

Datasheet


Molecular Formula

C30H49N9O9

Molecular Weight

679.8 g/mol

CAS Number

69558-55-0

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

THYMOPENTIN; 69558-55-0; Timunox; Arg-Lys-Asp-Val-Tyr; Sintomodulina

IUPAC/Chemical Name

(3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid

InChl Key

PSWFFKRAVBDQEG-YGQNSOCVSA-N

InChl Code

InChI=1S/C30H49N9O9/c1-16(2)24(28(46)38-22(29(47)48)14-17-8-10-18(40)11-9-17)39-27(45)21(15-23(41)42)37-26(44)20(7-3-4-12-31)36-25(43)19(32)6-5-13-35-30(33)34/h8-11,16,19-22,24,40H,3-7,12-15,31-32H2,1-2H3,(H,36,43)(H,37,44)(H,38,46)(H,39,45)(H,41,42)(H,47,48)(H4,33,34,35)/t19-,20-,21-,22-,24-/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/451417;

3D Conformer.

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