About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
THONZYLAMINE HCL exerts multiaxis biochemical modulation involving enzymaticcascade interference, receptormediated signalling adjustment, oxidativestress balancing, mitochondrialrespiratory modulation, ionchannel behaviour influence, cytoskeletalarchitecture modification and transcriptionfactor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membraneanchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP/DAG turnover, cAMP regulation, ATP flux and cellular redoxstate stability.
Benefits & Applications
- Receptorligand interaction and docking studies
- Kinase/catalytic pathway profiling
- Mitochondrial ATP/ROS functional modelling
- Multiomics integration research
- Cytoskeletal and membranedynamics analysis
- Apoptosis, autophagy and survivalpathway investigations
- SAR/QSAR modelling and molecular optimisation
Risks & Side Effects
- ROS accumulation and oxidativestress imbalance
- Mitochondrial overload or ETC suppression
- Ionchannel destabilisation (Ca²⁺/Na⁺/K⁺)
- Cytoskeletal disruption and membrane integrity loss
- Dosedependent cytotoxicity
- Inflammatory cascade activation
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C16H23ClN4O |
|---|---|
| Molecular Weight | 322.83 g/mol |
| CAS Number | 63-56-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Very soluble (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | THONZYLAMINE HYDROCHLORIDE; 63-56-9; Thonzylamine HCl; Anahist; Novohetramin |
| IUPAC/Chemical Name | N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine;hydrochloride |
| InChl Key | HRYJPHOTGFERGT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C16H22N4O.ClH/c1-19(2)11-12-20(16-17-9-4-10-18-16)13-14-5-7-15(21-3)8-6-14;/h4-10H,11-13H2,1-3H3;1H |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
