About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
SUXAMETHONIUM CHLORIDE (ID 27546) exhibits a highly distributed biochemical activity matrix spanning multi‑axis signalling disruption, enzymatic‑cascade interference, mitochondrial‑network recalibration, cytoskeletal remodelling, redox‑system modulation, ion‑flux redistribution and transcription‑factor pathway realignment. Its conformational topology enables interaction with catalytic cores, allosteric domains, transmembrane helices, hydrophobic receptor cavities, nucleotide‑binding pockets and multiprotein scaffolding structures. This generates system‑wide modulation across metabolic, genomic, structural and electrophysiological domains.
At the signalling level, SUXAMETHONIUM CHLORIDE may reshape phosphorylation gradients, modify propagation dynamics across MAPK/ERK/JNK/p38 axes, alter PI3K–AKT survival signalling, shift G‑protein coupling states, recalibrate intracellular Ca²⁺ microdomains, and modulate IP₃/DAG and cAMP‑PKA signalling amplitudes. Mitochondrial effects include ETC‑complex rebalancing, ATP‑turnover adjustment, ROS‑leakage threshold modulation and membrane‑potential polarity shifts. Its multi‑node regulation enables deep experimental interrogation of stress‑adaptation pathways and metabolic‑response thresholds.
High‑Resolution Research Applications
- Ultra‑scale kinome interference mapping & catalytic‑cascade simulation
- High‑fidelity receptor–ligand docking & conformational‑flow modelling
- Organelle cross‑talk modelling (UPR, mitochondrial/ER stress, mitophagy dynamics)
- Multi‑omics regulatory‑network reconstruction (RNA‑seq, metabolomics, proteomics, phosphoproteomics)
- Advanced cytoskeletal biomechanics (actin/tubulin turnover, tension‑mapping)
- Cell‑fate modelling across apoptosis, necroptosis, ferroptosis, parthanatos & autophagic flux axes
- AI‑enhanced SAR/QSAR molecular‑performance prediction
Toxicodynamics & Hazard Profile
- Accelerated ROS accumulation & antioxidant‑system saturation
- Mitochondrial fragmentation or ETC‑chain destabilisation
- Severe Ca²⁺/Na⁺/K⁺ ionic‑flux dysregulation
- Cytoskeletal depolymerisation & loss of mechanical integrity
- Membrane damage, permeability shifts & lipid‑bilayer thinning
- Inflammatory overactivation via NF‑κB, STAT & IRF signalling
- Multiple programmed‑cell‑death pathway activation
- Epigenetic distortions (methylation drift, acetylation imbalance)
For expert laboratory research only — not intended for biological exposure.
Datasheet
| Molecular Formula | C14H30Cl2N2O4 |
|---|---|
| Molecular Weight | 361.3 g/mol |
| CAS Number | 71-27-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Succinylcholine chloride; 71-27-2; Succinyldicholine chloride; Anectine; Midarine |
| IUPAC/Chemical Name | trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium dichloride |
| InChl Key | YOEWQQVKRJEPAE-UHFFFAOYSA-L |
| InChl Code | InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
