PROPANTHELINE BROMIDE
Propantheline bromide is an antimuscarinic agent that reduces gastric secretions and intestinal motility. It is used for peptic ulcer disease and GI spasms. Side effects include dry mouth, constipation, urinary retention, blurred vision, tachycardia, and heat intolerance. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
PROPANTHELINE BROMIDE demonstrates a highcomplexity biochemical interaction profile characterised by multilayer signalling integration, modular enzymatic pathway penetration, mitochondrial network modulation, ionflux recalibration, redoxstate equilibrium restructuring and transcriptionfactor axis reprogramming. Its molecular geometry enables conformational docking to catalytic pockets, allosteric domains, transmembrane receptor helices and cytoskeletal scaffolds, creating broad regulatory influence across metabolic, structural and genomic systems.
At the signalling level, PROPANTHELINE BROMIDE may modulate phosphorylation gradients, kinome cascade propagation (including MAPK, JNK, ERK, PI3KAKT, and AMPK axes), Gprotein subunit turnover, calcium wave propagation, secondary messenger amplification and stressadaptation thresholds. Mitochondrially, the compound can alter electrontransportchain efficiency, ATPADP cycling, mitochondrial ROS leakage, membrane potential polarity and respiratorycomplex activation ratios.
Advanced Research Value
PROPANTHELINE BROMIDE is particularly suited for:
- Crosspathway interference mapping and kinome interaction grids
- Ultrahigh resolution receptorligand docking and conformational prediction
- Organellestress modelling (ER stress, mitochondrial folding stress, autophagic flux modulation)
- Networklevel transcriptome rewiring using multiomics clustering
- Precision cytoskeletalmechanics analysis including actin polymerisation and tubulin turnover
- Apoptotic vs. survivalpathway bias quantification
- Advanced SAR, QSAR and machinelearning molecularperformance modelling
Risks, Toxicodynamics & Cellular Hazard Spectrum
At elevated exposure levels, PROPANTHELINE BROMIDE may induce:
- ROS surge and oxidative collapse
- Mitochondrial hyperfragmentation or respiratorycomplex shutdown
- Severe ionchannel destabilisation
- Cytoskeletal disassembly and membrane-integrity breach
- Aberrant transcriptionfactor activation, inflammatory bursts (NF-κB, STAT, IRF pathways)
- Highgrade apoptosis, necroptosis or ferroptosis initiation
- Epigenetic instability affecting methylation/acetylation balance
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C20H30BrNO4 |
|---|---|
| Molecular Weight | 448.4 g/mol |
| CAS Number | 50-34-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | PROPANTHELINE BROMIDE; 50-34-0; Pro-Banthine; Neometantyl; Ercotina |
| IUPAC/Chemical Name | methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium bromide |
| InChl Key | XLBIBBZXLMYSFF-UHFFFAOYSA-M |
| InChl Code | InChI=1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1 |
| References |
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