POLYINOSINIC ACID

Polyinosinic acid is a synthetic RNA polymer that stimulates immune responses through Tolllike receptor activation. It is used in research and experimental immunomodulation. Side effects include fever, malaise, inflammation, and cytokinerelated reactions depending on dose and route. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Scientific Overview

POLYINOSINIC ACID is a researchgrade biochemical compound used for advanced analytical, mechanistic and structural studies. It is often applied in laboratory environments requiring precise molecular behaviour, controlled pathway modulation and highfidelity reproducibility. The compound interacts with multiple biochemical systems depending on formulation, cell type and experimental conditions.

Mechanism of Action

Although the exact mechanism may vary by experimental model, POLYINOSINIC ACID typically exhibits activity involving:

  • Enzymatic pathway modulation through reversible or irreversible interaction with catalytic sites
  • Potential receptorlevel signaling effects influencing intracellular second messengers
  • Alterations in redox balance and oxidativestress handling systems
  • Mitochondrial functional modulation, including effects on ATP turnover and respiratorychain efficiency
  • Influence on transcriptional behaviour, geneexpression clusters and regulatory protein networks
  • Possible interaction with cytoskeletal structures affecting cellular stability and mechanical signaling

These combined effects make the compound suitable for multiaxis biochemical research.

Benefits and Applications

POLYINOSINIC ACID is commonly used for:

  • Pathway validation and mechanistic investigation
  • Bindingaffinity studies and structural modelling
  • Metabolicflux analysis and mitochondrialfunction profiling
  • Redox and oxidativestress research environments
  • Cytoskeletal and membranedynamic studies
  • Signaltransduction mapping across diverse biological systems

Risks and Safety Considerations

Potential risks associated with laboratory exposure include:

  • Oxidative imbalance or ROS accumulation
  • Mitochondrial stress or functional suppression at high concentrations
  • Unintended receptor or enzyme crossinteraction
  • Cytoskeletal destabilization or membrane disturbance
  • Dosedependent cytotoxicity under prolonged exposure

Handle only with appropriate laboratory biosafety protocols.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

(C10H11N4O7P)n

Molecular Weight

346.19 per monomer g/mol

CAS Number

30918-54-8

Storage Condition

Store at 2-8°C

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

IUPAC/Chemical Name

Polyinosinic acid RNA polymer

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

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