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Product Description
Mechanism of Action
PALLADIUM CHLORIDE (ID 27009) exhibits a multidimensional biochemical activity profile involving modulation of enzyme-catalyzed pathways, receptor-mediated intracellular signaling, ion-channel regulation, mitochondrial bioenergetics, oxidative-stress balancing, membrane dynamics, and transcription-factor orchestration. Its molecular configuration allows high-affinity interaction with catalytic residues, allosteric domains, regulatory scaffolds, and signaling intermediates, influencing phosphorylation cycles, second‑messenger flux (Ca²⁺, cAMP, IP₃, DAG), ROS equilibrium, ATP synthesis, and mitochondrial respiratory-chain regulation.
Depending on dose, exposure duration, and cell type, PALLADIUM CHLORIDE can modify chromatin accessibility, metabolic flux routing, vesicular trafficking, cytoskeletal structure, and gene-expression clusters associated with survival, inflammation, apoptosis, autophagy, and metabolic adaptation.
Benefits and Advantages
Due to its consistent mechanistic behavior, this compound is utilized in advanced research, including:
- Receptor–ligand interaction studies and affinity modeling
- High‑resolution enzyme kinetics and catalytic-pathway deconstruction
- Mitochondrial ATP‑flux assays and oxidative‑stress system modeling
- Multi‑omics profiling (transcriptomics, proteomics, metabolomics, phosphoproteomics)
- Cytoskeletal and membrane‑dynamics exploration
- Apoptosis, ferroptosis, necroptosis, and autophagy pathway analysis
- Structure–activity relationship (SAR) investigations and compound optimization
- Pharmacodynamic modeling, mechanistic dose–response scaling, and pathway benchmarking
Side Effects and Risks
Potential laboratory risks include:
- Oxidative‑stress imbalance and ROS accumulation
- Mitochondrial overload or respiratory-chain suppression
- Ion‑channel dysregulation affecting Ca²⁺/Na⁺/K⁺ homeostasis
- Unintended receptor cross‑activation or pathway inhibition
- Cytoskeletal destabilization and membrane‑integrity disruption
- Dose-dependent cytotoxicity (apoptotic or autophagic induction)
- Transcriptional or epigenetic instability under prolonged exposure
- Activation of inflammatory signaling networks (NF‑κB, JNK, p38 MAPK)
Use strictly in controlled laboratory environments with appropriate biosafety protocols.
Datasheet
| Molecular Formula | Cl2Pd |
|---|---|
| Molecular Weight | 177.32 g/mol |
| CAS Number | 2099324 |
| Storage Condition | Keep tightly closed. /Dihydrate/ |
| Solubility | Soluble (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Palladium(II) chloride; Palladium chloride; 7647-10-1; Dichloropalladium; Palladium dichloride |
| IUPAC/Chemical Name | dichloropalladium |
| InChl Key | PIBWKRNGBLPSSY-UHFFFAOYSA-L |
| InChl Code | InChI=1S/2ClH.Pd/h2*1H;/q;;+2/p-2 |
| References |
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