About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
MINOCYCLINE HCL exhibits a deeply layered biochemical action profile involving coordinated modulation of enzyme-driven catalytic cascades, receptor-mediated signalling processes, intracellular ion dynamics, mitochondrial bioenergetics, membrane-potential stability and transcription-factor pathway regulation. Its molecular architecture supports high-affinity interaction with both catalytic and regulatory protein domains. These interactions allow the compound to influence phosphorylationdephosphorylation cycles, reactive oxygen species (ROS) equilibrium, ATP turnover, calcium flux, and mitochondrial redox-state balance. In many experimental systems, MINOCYCLINE HCL contributes to structural-protein reorganisation, cytoskeletal tension modulation and vesicular transport behaviour.
The compound may also affect chromatin accessibility and epigenetic markers, shifting transcriptional activity across multiple gene clusters involved in stress adaptation, metabolic steering and survival signalling. Such multi-dimensional mechanistic behaviour underlies its utility in complex research models.
Benefits and Advantages
MINOCYCLINE HCL is suitable for a wide range of advanced laboratory , including:
- Detailed receptorligand interaction mapping and affinity-modelling
- High-resolution enzymatic kinetic analysis and catalytic cascade mapping
- Mitochondrial-function assays, ATP-flux modelling and oxidative-stress monitoring
- Multi-omics systems: transcriptomics, proteomics, metabolomics and phosphoproteomics
- Cytoskeletal-dynamics research including actintubulin remodelling and mechanical signalling
- Apoptosis, necroptosis, ferroptosis and autophagy signalling studies
- SAR (structureactivity relationship) development and molecular-performance optimisation
- Advanced pharmacodynamic simulations and doseresponse mechanistic modelling
Side Effects and Risks
Potential risks associated with MINOCYCLINE HCL include:
- Oxidative-stress imbalance leading to ROS accumulation
- Mitochondrial overactivation or suppression of respiratory-chain complexes
- Ion-channel dysregulation affecting Ca²⁺/Na⁺/K⁺ homeostasis
- Unintended receptor cross-activation or inhibition
- Cytoskeletal destabilisation and membrane-integrity compromise
- Dose-dependent cytotoxicity, apoptosis, autophagy or metabolic-collapse signalling
- Activation of inflammatory transcriptional programmes (e.g., NF-κB, p38 MAPK, JNK)
Prolonged exposure or excessive concentration may trigger transcriptional rewiring, altered metabolic routing, organelle stress responses, or epigenetic instability. Handle only under controlled laboratory conditions with appropriate biosafety procedures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C23H27ClN3O7 |
|---|---|
| Molecular Weight | 493.9 g/mol |
| CAS Number | 13614-98-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | MINOCYCLINE HYDROCHLORIDE; 13614-98-7; Minocycline HCl; Arestin; Minomycin |
| IUPAC/Chemical Name | (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride |
| InChl Key | WTJXVDPDEQKTCV-VQAITOIOSA-N |
| InChl Code | InChI=1S/C23H27N3O7.ClH/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28;/h5-6,9,11,17,27-28,31,33H,7-8H2,1-4H3,(H2,24,32);1H/t9-,11-,17-,23-;/m0./s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
