METOPROLOL TARTRATE
Metoprolol tartrate is a selective 1-blocker reducing heart rate and blood pressure. Benefits include improved angina, rhythm control, and hypertension management. Side effects include fatigue, bradycardia, and dizziness. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
METOPROLOL TARTRATE demonstrates an extensive, multiaxis biochemical activity profile involving coordinated modulation of receptormediated signalling, enzymeregulated catalytic cascades, mitochondrial bioenergetics, intracellular ion regulation, and transcriptomic pathway dynamics. Its physicochemical properties support highaffinity interactions with both catalytic and regulatory protein domains, enabling interference with phosphorylationdephosphorylation cycles, secondmessenger turnover (cAMP, IP, DAG, Ca²⁺), and redoxequilibrium systems.
In cellular environments, METOPROLOL TARTRATE may influence mitochondrial membrane potential, ATP synthesis efficiency, ROS generation and antioxidant neutralisation capacity. In addition, structuralprotein interactions can modify cytoskeletal arrangement, impacting cell motility, vesicular trafficking, and mechanical signalling. The compound may further modulate chromatin accessibility, transcription factor binding profiles, epigenetic markers, and geneexpression stability.
Benefits and Advantages
Because of its reproducible biochemical footprint, METOPROLOL TARTRATE is an important tool across advanced research domains, including:
- Detailed receptorligand binding analysis and structural docking validation
- Highdefinition enzyme kinetics and catalyticdomain pathway mapping
- Mitochondrial respiration modelling, ATPflux analysis and oxidativestress pathway evaluation
- Transcriptomic, proteomic and metabolomic integration studies for fullpathway profiling
- Apoptosis, necroptosis and autophagyrelated signalling research
- Cytoskeletaldynamics studies involving actin, tubulin and intermediate filaments
- Highresolution SAR (structureactivity relationship) investigations for molecular optimisation
- Pharmacodynamic modelling for doseresponse, thresholdactivation and mechanistic benchmarking
Side Effects and Risks
Potential risks include:
- Redox imbalance and excessive ROS accumulation
- Mitochondrial overload or respiratorychain suppression
- Transcriptional pathway disruption or epigenetic instability
- Interference with ionchannel behaviour and calciumhandling regulation
- Cytoskeletal destabilisation and impaired membrane integrity
- Dosedependent cytotoxicity, apoptosis or autophagy induction
- Activation of inflammatory signalling cascades such as NF-κB, JNK, or p38
Extended exposure or elevated dosing may trigger metabolic rewiring, organelle stress responses, or longterm alterations in cellular signalling architecture. Strict biosafety protocols, controlled handling, and regulated exposure windows are required.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C15H25NO3·C4H6O6 |
|---|---|
| Molecular Weight | 684.8 g/mol |
| CAS Number | 56392-17-7 |
| Storage Condition | Commercially available preparations of metoprolol tartrate should be protected from light. Metoprolol tartrate tablets should be stored in tight, light-resistant containers at 15-30 °C and metoprolol tartrate injection should be stored at a temperature of 30 °C or less, preferably at 15-30 °C, freezing of the injection should be avoided. |
| Solubility | Soluble (tartrate form) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Metoprolol tartrate; 56392-17-7; Beloc; Betaloc; Lopresor |
| IUPAC/Chemical Name | (2R,3R)-2,3-dihydroxybutanedioic acid;bis(1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol) |
| InChl Key | YGULWPYYGQCFMP-CEAXSRTFSA-N |
| InChl Code | InChI=1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1 |
| References |
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