About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
MEMANTINE displays a broad and multiaxis biochemical interaction profile characterised by modulation of enzymatic networks, receptormediated signalling, intracellular ion regulation, mitochondrial bioenergetics and transcriptional pathway governance. Its structural features suggest interactions with catalytic and regulatory proteins, leading to changes in phosphorylation cycles, metabolic flux, mitochondrial redox balance, calciumsignalling behaviour and stressresponse activation. Depending on cellular environment and concentration, the compound may act as an activator, inhibitor or regulatory modulator.
Benefits and Advantages
This compound supports a wide range of , including:
- Receptorligand affinity profiling and bindingsite mapping
- Enzymecascade modelling and catalyticdomain interaction studies
- Mitochondrialfunction assays, oxidativestress evaluation and metabolicflux tracking
- Transcriptomic, proteomic and metabolomic investigation for pathway mapping
- Apoptosis / autophagy pathway research and cellularstress modelling
- Highresolution mechanismofaction studies and SAR exploration
Side Effects and Risks
Potential risks include oxidative imbalance, mitochondrial overload, ionchannel dysregulation, receptor crosstalk, cytoskeletal disruption and dosedependent cytotoxicity. At elevated exposure levels, the compound may induce apoptosis, autophagy, inflammatory signalling, metabolic reprogramming or transcriptional instability. Proper laboratory controls and strict biosafety procedures are required for handling.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C12H21N |
|---|---|
| Molecular Weight | 179.30 g/mol |
| CAS Number | 19982-08-2 |
| Storage Condition | Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. |
| Solubility | soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | memantine; 19982-08-2; 3,5-dimethyladamantan-1-amine; 1-Amino-3,5-dimethyladamantane; Memantina |
| IUPAC/Chemical Name | 3,5-dimethyladamantan-1-amine |
| InChl Key | BUGYDGFZZOZRHP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3 |
| References |
3D Conformer.
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