MEBENZONIUM IODIDE
Mebenzonium iodide is a quaternary ammonium anticholinesterase inhibitor that enhances neuromuscular transmission in myasthenia gravis. Benefits include improved muscle strength. Side effects include abdominal cramps, salivation, sweating, bradycardia, and cholinergic symptoms. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
MEBENZONIUM IODIDE exhibits a multilayered biochemical interaction profile involving modulation of enzyme cascades, receptorregulated signalling, mitochondrial bioenergetics, redoxstate equilibrium, membranepotential dynamics and transcriptionfactor activation. Depending on concentration and cellular context, the compound can influence phosphorylation cycles, alter calcium signalling thresholds, disrupt or stabilise cytoskeletal structures, and reprogram metabolic flux pathways.
Benefits and Advantages
This compound is widely used in advanced mechanistic research, including:
- Receptorligand interaction analysis and allostericbinding studies
- Enzymekinetic mapping and catalyticdomain investigation
- Mitochondrialfunction, ROSbalance and redoxmodulation assays
- Transcriptomic, proteomic and metabolomic profiling
- Cellularstress signalling, apoptosis/autophagy modelling and membranedynamics studies
- Pharmacodynamic simulation, SAR evaluation and earlystage compound screening
Side Effects and Risks
Possible risks include mitochondrial overload, oxidativestress imbalance, ionchannel disruption, metabolic pathway misregulation, receptor crosstalk, and dosedependent cytotoxicity. At higher exposure, apoptosis, autophagy, transcriptional destabilisation or inflammationpathway activation may occur. Use only with strict laboratory safety procedures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C19H40I2N2 |
|---|---|
| Molecular Weight | 550.3 g/mol |
| CAS Number | 7681-78-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Mebezonium Iodide; 7681-78-9; Ioduro de mebezonio; Iodure de mebezonium; Mebezonio ioduro |
| IUPAC/Chemical Name | trimethyl-[4-[[4-(trimethylazaniumyl)cyclohexyl]methyl]cyclohexyl]azanium diiodide |
| InChl Key | CWPAAKNARYMZLM-UHFFFAOYSA-L |
| InChl Code | InChI=1S/C19H40N2.2HI/c1-20(2,3)18-11-7-16(8-12-18)15-17-9-13-19(14-10-17)21(4,5)6;;/h16-19H,7-15H2,1-6H3;2*1H/q+2;;/p-2 |
| References |
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