About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
LEVONORDEFRIN demonstrates a highcomplexity biochemical profile involving modulation of receptor systems, enzymeregulated metabolic pathways, mitochondrial performance, intracellular ion dynamics and transcriptionlevel regulation. Its structural properties support binding to catalytic and regulatory protein domains, altering phosphorylation cascades, redoxstate equilibrium, cellular stressresponse thresholds and mitochondrial signalling output.
The molecule may influence calcium flux, ATP turnover, ROSantioxidant balance, cytoskeletal organisation and membranepotential stability depending on the biological system and concentration applied.
Benefits and Advantages
Widely applied in mechanistic and pharmacodynamic research, including:
- Receptorligand interaction analysis and affinity profiling
- Enzymekinetic and catalyticpathway investigations
- Mitochondrialfunction, metabolicflux and oxidativestress studies
- Multiomics research: transcriptomics, proteomics and metabolomics
- Cellstress signalling, apoptosis/autophagy modelling and cytoskeletaldynamics mapping
- Preclinical screening, SAR modelling and comparative mechanistic benchmarking
Side Effects and Risks
Potential risks include oxidative imbalance, mitochondrial strain, unintended receptor crossactivation, ionchannel perturbation, metabolic rewiring, and dosedependent cytotoxicity. High exposure may induce apoptosis, autophagy, inflammatory signalling or transcriptional destabilisation. Strict laboratory safety protocols and controlled handling conditions are required.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C9H13NO3 |
|---|---|
| Molecular Weight | 183.20 g/mol |
| CAS Number | 829-74-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | levonordefrin; 829-74-3; Corbadrine; Neo-Cobefrin; Corbadrina |
| IUPAC/Chemical Name | 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol |
| InChl Key | GEFQWZLICWMTKF-CDUCUWFYSA-N |
| InChl Code | InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1 |
| References |
3D Conformer.
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