IODOQUINOL

Iodoquinol is an antiamoebic agent acting locally in the intestine. Side effects include nausea, abdominal cramps, and rare optic neuropathy. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 2909abb26654 Category: Tag:

Product Description


Mechanism of Action

IODOQUINOL exhibits complex multipathway biochemical interactions involving receptorlevel modulation, regulatory enzyme interference, intracellular signalling adjustment and transcriptomic pathway influence. Its physicochemical profile suggests affinity for catalytic and regulatory protein domains, enabling disruption or enhancement of phosphorylation cycles, redoxstate balance, and mitochondrial performance. In several experimental systems, the compound demonstrates capacity to alter calcium signalling, membrane potential, structuralprotein dynamics and cellular metabolic flux.

Benefits and Advantages

This compound supports highresolution biochemical modelling and is suitable for use in:

  • Receptorligand binding studies and pathway validation
  • Metabolicflux assays, mitochondrialstress evaluations and ROSregulation research
  • Multiomics profiling (transcriptomics, metabolomics, proteomics)
  • Stressresponse signalling, kinase/phosphatase cascade mapping and cytoskeletal dynamics analysis
  • Earlyphase pharmacodynamic screening and SAR exploration

Side Effects and Risks

Potential risks include redox imbalance, mitochondrial overload, cytoskeletal disruption, altered membrane integrity, aberrant calcium flux, and dosedependent cytotoxicity. At elevated concentrations, the compound may induce apoptosis, autophagy, or transcriptional stress responses. Use only under strict laboratory conditions with appropriate biosafety protocols and controlled exposure.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C9H5I2NO

Molecular Weight

396.95 g/mol

CAS Number

83-73-8

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

ALMOST INSOL IN WATER; SPARINGLY SOL IN ALCOHOL, ETHER, ACETONE; SOL IN HOT PYRIDINE & HOT DIOXANE

Purity

Purity information is available upon request (COA).

Synonym

iodoquinol; 83-73-8; Diiodohydroxyquinoline; 5,7-diiodoquinolin-8-ol; 5,7-Diiodo-8-hydroxyquinoline

IUPAC/Chemical Name

5,7-diiodoquinolin-8-ol

InChl Key

UXZFQZANDVDGMM-UHFFFAOYSA-N

InChl Code

InChI=1S/C9H5I2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

References

https://pubchem.ncbi.nlm.nih.gov/compound/3728;

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