IODOFENPHOS
Iodofenphos is an organophosphate pesticide that inhibits cholinesterase activity, disrupting nerve signaling in insects. Side effects include cholinergic symptoms, respiratory irritation, and toxicity upon significant exposure. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
IODOFENPHOS exhibits complex multipathway biochemical interactions involving receptorlevel modulation, regulatory enzyme interference, intracellular signalling adjustment and transcriptomic pathway influence. Its physicochemical profile suggests affinity for catalytic and regulatory protein domains, enabling disruption or enhancement of phosphorylation cycles, redoxstate balance, and mitochondrial performance. In several experimental systems, the compound demonstrates capacity to alter calcium signalling, membrane potential, structuralprotein dynamics and cellular metabolic flux.
Benefits and Advantages
This compound supports highresolution biochemical modelling and is suitable for use in:
- Receptorligand binding studies and pathway validation
- Metabolicflux assays, mitochondrialstress evaluations and ROSregulation research
- Multiomics profiling (transcriptomics, metabolomics, proteomics)
- Stressresponse signalling, kinase/phosphatase cascade mapping and cytoskeletal dynamics analysis
- Earlyphase pharmacodynamic screening and SAR exploration
Side Effects and Risks
Potential risks include redox imbalance, mitochondrial overload, cytoskeletal disruption, altered membrane integrity, aberrant calcium flux, and dosedependent cytotoxicity. At elevated concentrations, the compound may induce apoptosis, autophagy, or transcriptional stress responses. Use only under strict laboratory conditions with appropriate biosafety protocols and controlled exposure.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C8H8Cl2IO3PS |
|---|---|
| Molecular Weight | 413.00 g/mol |
| CAS Number | 18181-70-9 |
| Storage Condition | … MUST BE STORED IN ITS SEALED ORIGINAL CONTAINERS, IN WELL-AIRED, FRESH & DRY STOREHOUSES OR IN SHADED & POSSIBLY WELL-AIRED PLACES. IT IS RECOMMENDED THAT THE PRODUCT'S TEMP … NOT EXCEED 25-30 °C, & KEEP … AWAY FROM SOURCES OF HEAT, FREE FLAMES, OR SPARK-GENERATING EQUIPMENT. CONTAINERS MUST BE STACKED IN SUCH A WAY AS TO PERMIT FREE CIRCULATION OF AIR … AT BOTTOM & INSIDE OF PILES. STORAGE AREAS MUST BE LOCATED AT SUITABLE DISTANCE FROM INHABITED BUILDINGS, ANIMAL SHELTERS, & FOOD STORES; MOREOVER, THEY MUST BE INACCESSIBLE TO UNAUTHORIZED PERSONS, CHILDREN, & DOMESTIC ANIMALS. |
| Solubility | AT 20 °C: <2 MG/L WATER; 450 G/L ACETONE, TOLUENE; 810 G/L DICHLOROMETHANE; 30 G/L METHANOL, OCTAN-1-OL |
| Purity | Purity information is available upon request (COA). |
| Synonym | IODOFENPHOS; Jodfenphos; 18181-70-9; Alfacron; Iodofenfos |
| IUPAC/Chemical Name | (2,5-dichloro-4-iodophenoxy)-dimethoxy-sulfanylidene-lambda5-phosphane |
| InChl Key | LFVLUOAHQIVABZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H8Cl2IO3PS/c1-12-15(16,13-2)14-8-4-5(9)7(11)3-6(8)10/h3-4H,1-2H3 |
| References |
3D Conformer.
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