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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
IDOXURIDINE (ID 26402) exhibits a multi-dimensional biochemical activity profile that affects cellular regulation at enzyme, receptor, and transcriptional levels. Its molecular interactions can alter phosphorylation cycles, modulate ionic homeostasis, influence mitochondrial respiration, and adjust redox-signaling pathways. Structural properties suggest specific affinity for regulatory proteins, enabling modulation of metabolic flux and cellular response thresholds.
Benefits and Advantages
This compound is suited for high-resolution mechanistic research, multi‑omics integration studies, receptor-binding experiments, enzyme-pathway mapping, and advanced pharmacodynamic modelling. It supports ROS-regulation assays, signalling-cascade analysis, cytoskeletal‑dynamics research, and metabolic adaptation models. Due to predictable biochemical behaviour, it is often used as a comparative reference in pathway‑perturbation studies.
- Useful in mechanistic pharmacology and biochemical modelling
- Applicable in oxidative-stress, mitochondrial-function and signalling studies
- Reliable for transcriptional and proteomic profiling
- Supports SAR (structure–activity relationship) investigations
Side Effects and Risks
Potential risks include mitochondrial overload, ROS imbalance, inadvertent receptor cross‑talk, disruption of ion-channel dynamics, and dose-dependent cytotoxicity. High exposure may trigger apoptosis, autophagy, or cellular stress-response activation. Controlled handling conditions and biosafety protocols are required for laboratory use.
Datasheet
| Molecular Formula | C9H11IN2O5 |
|---|---|
| Molecular Weight | 354.10 g/mol |
| CAS Number | 54-42-2 |
| Storage Condition | Store between 2 and 8 °C (36 and 46 °F). Store in a tight, light-resistant container. /Ophthalmic Solution USP/ |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | idoxuridine; 5-Iodo-2'-deoxyuridine; 54-42-2; 5-Iododeoxyuridine; Idoxuridin |
| IUPAC/Chemical Name | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione |
| InChl Key | XQFRJNBWHJMXHO-RRKCRQDMSA-N |
| InChl Code | InChI=1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1 |
| References |
3D Conformer.
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