HEMIN

Hemin is an iron-containing porphyrin used to treat acute porphyria by inhibiting ALA synthase. Benefits include reduced neurotoxic metabolite production. Side effects include phlebitis, headache, and iron overload risks.

SKU: c874fa3da2a0 Category: Tag:

Product Description


Mechanism of Action

This compound (ID 26325) exhibits a multifaceted biochemical activity profile involving receptor-level modulation, enzyme-pathway interference, and intracellular signalling adjustments. It can alter phosphorylation dynamics, metabolic flux balance, mitochondrial function, and the regulation of adaptive stress-response pathways.

Benefits and Advantages

Suitable for mechanistic pathway research, multi‑omics profiling, receptor-binding investigations, metabolic modelling, and experimental systems requiring controlled biochemical perturbation. Its predictable interaction patterns make it reliable for pharmacodynamic benchmarking and preclinical assay calibration.

Side Effects and Risks

Potential risks include oxidative stress imbalance, cytoskeletal disruption, unintended receptor crosstalk, dose‑dependent cytotoxicity, and overstimulation or suppression of regulatory pathways. Laboratory use only with appropriate biosafety precautions.

Datasheet


Molecular Formula

C34H32ClFeN4O4

Molecular Weight

651.9 g/mol

CAS Number

16009-13-5

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

RefChem:1093269; Npc76529; hemin; Chlorohemin; Panhematin

IUPAC/Chemical Name

3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(3+);chloride

InChl Key

BTIJJDXEELBZFS-UHFFFAOYSA-K

InChl Code

InChI=1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3

References

https://pubchem.ncbi.nlm.nih.gov/compound/455658;

3D Conformer.

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