GLIPIZIDE

Glipizide is a sulfonylurea that lowers blood glucose by stimulating beta‑cell insulin release. Side effects include hypoglycemia, headache, and GI discomfort.

SKU: e791f5ee65dc Category: Tag:

Product Description


Mechanism of Action

Glipizide is a sulfonylurea that binds SUR1 on pancreatic KATP channels, enhancing insulin secretion from beta cells and improving glucose control.

Benefits and Advantages

Used in pancreatic-islet research, insulin-secretion modelling, metabolic studies and endocrine pharmacology.

Side Effects and Risks

Hypoglycemia, weight gain and rare cholestatic reactions.

Datasheet


Molecular Formula

C21H27N5O4S

Molecular Weight

445.5 g/mol

CAS Number

29094-61-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

glipizide; 29094-61-9; Glucotrol; Glydiazinamide; Glibenese

IUPAC/Chemical Name

N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide

InChl Key

ZJJXGWJIGJFDTL-UHFFFAOYSA-N

InChl Code

InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3478;

3D Conformer.

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