GLIMEPIRIDE

Glimepiride enhances insulin release and improves peripheral glucose uptake. Side effects include hypoglycemia, dizziness, and weight gain. Only GMP materials will be supplied, logistics all according to GDP.

SKU: f33069353027 Category: Tag:

Product Description


Mechanism of Action

Glimepiride stimulates insulin release through K⁺ATP-channel closure and enhances peripheral glucose uptake via insulin-sensitizing secondary pathways.

Benefits and Advantages

Used in glucose-regulation studies, sulfonylurea SAR work, metabolic modelling and beta-cell function assays.

Side Effects and Risks

Hypoglycemia, dizziness and hepatic enzyme elevation.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C24H34N4O5S

Molecular Weight

490.6 g/mol

CAS Number

93479-97-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

3.84e-02 g/L

Purity

Purity information is available upon request (COA).

Synonym

1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-; 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-2-4-(trans-4-methylcyclohexyl)aminocarbonylaminosulfonylphenylethyl-2-oxo-; 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-(2-(4-(((((trans-4-methylcyclohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo-; RefChem:439179; glimepiride

IUPAC/Chemical Name

4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide

InChl Key

WIGIZIANZCJQQY-UHFFFAOYSA-N

InChl Code

InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3476;

3D Conformer.

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