GLICLAZIDE

Gliclazide stimulates pancreatic insulin secretion with lower hypoglycemia risk than some sulfonylureas. Side effects include dizziness, nausea, and mild weight gain. Only GMP materials will be supplied, logistics all according to GDP.

SKU: dba0e32dc998 Category: Tag:

Product Description


Mechanism of Action

Gliclazide is a second-generation sulfonylurea that stimulates insulin secretion via K⁺ATP-channel inhibition and exerts additional antioxidant and vascular-protective effects.

Benefits and Advantages

Used in diabetes-pathway studies, beta-cell signalling assays and insulin-modulation research.

Side Effects and Risks

Hypoglycemia, nausea and weight changes.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H21N3O3S

Molecular Weight

323.4 g/mol

CAS Number

21187-98-4

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

1.90e-01 g/L

Purity

Purity information is available upon request (COA).

Synonym

gliclazide; 21187-98-4; Glimicron; Diamicron; Gliclazida

IUPAC/Chemical Name

1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea

InChl Key

BOVGTQGAOIONJV-UHFFFAOYSA-N

InChl Code

InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3475;

3D Conformer.

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