GLICLAZIDE

Gliclazide stimulates pancreatic insulin secretion with lower hypoglycemia risk than some sulfonylureas. Side effects include dizziness, nausea, and mild weight gain.

SKU: dba0e32dc998 Category: Tag:

Product Description


Mechanism of Action

Gliclazide is a second-generation sulfonylurea that stimulates insulin secretion via KATP-channel inhibition and exerts additional antioxidant and vascular-protective effects.

Benefits and Advantages

Used in diabetes-pathway studies, beta-cell signalling assays and insulin-modulation research.

Side Effects and Risks

Hypoglycemia, nausea and weight changes.

Datasheet


Molecular Formula

C15H21N3O3S

Molecular Weight

323.4 g/mol

CAS Number

21187-98-4

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

1.90e-01 g/L

Purity

Purity information is available upon request (COA).

Synonym

gliclazide; 21187-98-4; Glimicron; Diamicron; Gliclazida

IUPAC/Chemical Name

1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea

InChl Key

BOVGTQGAOIONJV-UHFFFAOYSA-N

InChl Code

InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3475;

3D Conformer.

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