GESTODENE

Gestodene is a potent progestin used in hormonal contraceptives. Side effects include breakthrough bleeding, breast tenderness, and thrombotic risk.

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Product Description


Mechanism of Action

Gestodene is a potent progestogen that binds progesterone receptors, influencing transcription of reproductive and endocrine genes, suppressing ovulation and altering cervical mucus and endometrial activity.

Benefits and Advantages

Used in hormone-pathway studies, receptor-binding assays, endocrine research and contraceptive-modelling systems.

Side Effects and Risks

Thromboembolic risk, hormonal imbalance, mood changes and metabolic effects.

Datasheet


Molecular Formula

C21H26O2

Molecular Weight

310.4 g/mol

CAS Number

60282-87-3

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

GESTODENE; 60282-87-3; Gestoden; Gestodeno; SH B 331

IUPAC/Chemical Name

(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one

InChl Key

SIGSPDASOTUPFS-XUDSTZEESA-N

InChl Code

InChI=1S/C21H26O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,10,12-13,16-19,23H,3,5-9,11H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/3033968;

3D Conformer.

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