GEMFIBROZIL
Gemfibrozil activates PPAR to lower triglycerides and raise HDL. Side effects include gallstones, GI upset, and muscle pain. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Gemfibrozil activates PPAR-, altering transcription of genes involved in fatty-acid oxidation and lipoprotein metabolism, reducing triglycerides and modulating HDL levels.
Benefits and Advantages
Used in lipid-metabolism studies, PPAR- signalling assays, metabolic syndrome modelling and dyslipidemia research.
Side Effects and Risks
Risk of gallstones, GI upset, liver enzyme elevation and myopathy (especially with statins).
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C15H22O3 |
|---|---|
| Molecular Weight | 250.33 g/mol |
| CAS Number | 25812-30-0 |
| Storage Condition | Commercially available gemfibrozil tablets should be stored in tight containers at a temperature less than 30 °C. |
| Solubility | 2.78e-02 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | gemfibrozil; 25812-30-0; 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid; Lopid; Jezil |
| IUPAC/Chemical Name | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid |
| InChl Key | HEMJJKBWTPKOJG-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17) |
| References |
3D Conformer.
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