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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Furizazole is an imidazole‑like azole antifungal with a nitrofuran moiety that inhibits fungal cytochrome P450‑dependent 14‑α‑demethylase, blocking ergosterol biosynthesis and compromising cell‑membrane integrity. Additional nitrofuran‑based redox activity contributes to fungistatic or fungicidal effects.
Benefits and Advantages
Used in ergosterol‑pathway research, azole SAR studies, fungal redox‑stress modelling and combination antifungal testing.
Side Effects and Risks
Potential hepatic enzyme elevation, GI disturbances, skin reactions and nitrofuran‑associated genotoxicity concerns. Handle with azole‑nitrofuran dual‑mechanism precautions.
Datasheet
| Molecular Formula | C10H6Cl2N2O |
|---|---|
| Molecular Weight | 278.13 g/mol |
| CAS Number | 121776-33-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Furilazole; 121776-33-8; MON 13900; 3-(Dichloroacetyl)-5-(2-furanyl)-2,2-dimethyloxazolidine; Furilazole [ISO:BSI] |
| IUPAC/Chemical Name | 2,2-dichloro-1-[5-(furan-2-yl)-2,2-dimethyl-1,3-oxazolidin-3-yl]ethanone |
| InChl Key | MCNOFYBITGAAGM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C11H13Cl2NO3/c1-11(2)14(10(15)9(12)13)6-8(17-11)7-4-3-5-16-7/h3-5,8-9H,6H2,1-2H3 |
| References |
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