About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Ftorafur (tegafur) is a prodrug of 5‑fluorouracil that undergoes CYP‑mediated activation, gradually releasing 5‑FU to inhibit thymidylate synthase and RNA/DNA synthesis.
Benefits and Advantages
Used in prodrug‑activation studies, oncologic cytotoxicity assays, TS‑inhibition modelling and combination‑therapy research.
Side Effects and Risks
Myelosuppression, GI toxicity, neurotoxicity and dermatologic reactions.
Datasheet
| Molecular Formula | C8H9FN2O3 |
|---|---|
| Molecular Weight | 200.17 g/mol |
| CAS Number | 17902-23-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Partly miscible |
| Purity | Purity information is available upon request (COA). |
| Synonym | tegafur; 17902-23-7; Ftorafur; Futraful; Sinoflurol |
| IUPAC/Chemical Name | 5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione |
| InChl Key | WFWLQNSHRPWKFK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
