FLUTICASONE PROPIONATE

Fluticasone propionate is an inhaled corticosteroid reducing airway inflammation in asthma. Side effects include hoarseness, oral thrush, and throat irritation. Only GMP materials will be supplied, logistics all according to GDP.

SKU: b1e3a54d57dd Category: Tag:

Product Description


Mechanism of Action

Fluticasone propionate is a potent inhaled glucocorticoid that suppresses airway inflammation by inhibiting NF-κB and cytokine transcription.

Benefits and Advantages

Used in asthma models, inhalationdrug development and mucosalimmune regulation studies.

Side Effects and Risks

Oropharyngeal candidiasis, hoarseness and adrenal suppression.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C25H31F3O5S

Molecular Weight

500.6 g/mol

CAS Number

80474-14-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Insoluble

Purity

Purity information is available upon request (COA).

Synonym

FLUTICASONE PROPIONATE; 80474-14-2; Flovent; Cutivate; Flixotide

IUPAC/Chemical Name

[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

InChl Key

WMWTYOKRWGGJOA-CENSZEJFSA-N

InChl Code

InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/444036;

3D Conformer.

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