FLURANDRENOLIDE
Flurandrenolide is a topical corticosteroid reducing inflammatory skin conditions. Side effects include burning, atrophy, and telangiectasia.
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Product Description
Mechanism of Action
Flurandrenolide is a corticosteroid that decreases inflammatory mediator synthesis and inhibits leukocyte infiltration.
Benefits and Advantages
Used in dermatologic models, corticosteroid‑receptor research and topical formulation development.
Side Effects and Risks
Skin thinning, adrenal suppression, irritation and dyschromia.
Datasheet
| Molecular Formula | C24H33FO6 |
|---|---|
| Molecular Weight | 436.5 g/mol |
| CAS Number | 1524-88-5 |
| Storage Condition | Flurandrenolide cream, lotion, and ointment should be protected from light and stored in tight containers at a temperature less than 40 °C, preferably between 15-30 °C; freezing should be avoided. Flurandrenolide tape should be stored at 15-30 °C. |
| Solubility | Insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | flurandrenolide; Fludroxycortide; 1524-88-5; Flurandrenolone; Cordran |
| IUPAC/Chemical Name | (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one |
| InChl Key | POPFMWWJOGLOIF-XWCQMRHXSA-N |
| InChl Code | InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1 |
| References |
3D Conformer.
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