FLUOROMETHOLONE ACETATE
Fluorometholone acetate provides enhanced ocular penetration for stronger anti‑inflammatory action. Side effects include elevated intraocular pressure, irritation, and risk of cataract formation with long-term use.
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Product Description
Mechanism of Action
Fluorometholone acetate is a more lipophilic ester form with enhanced ocular penetration and prolonged corticosteroid activity.
Benefits and Advantages
Used in advanced ophthalmic formulation studies, GR‑pathway modelling and ocular‑inflammation suppression experiments.
Side Effects and Risks
Similar to base form: IOP elevation, cataract risk and immunosuppression.
Datasheet
| Molecular Formula | C24H31FO5 |
|---|---|
| Molecular Weight | 418.5 g/mol |
| CAS Number | 694485 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | FLUOROMETHOLONE ACETATE; Eflone; 3801-06-7; Fluorometholone 17-acetate; Flarex |
| IUPAC/Chemical Name | [(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate |
| InChl Key | YRFXGQHBPBMFHW-SBTZIJSASA-N |
| InChl Code | InChI=1S/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1 |
| References |
3D Conformer.
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