FLUORAURACIL
Fluorouracil is a pyrimidine analogue inhibiting thymidylate synthase, used in cancers. Side effects include myelosuppression, mucositis, and photosensitivity.
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Product Description
Mechanism of Action
Fluorouracil (5‑FU) inhibits thymidylate synthase and incorporates into RNA and DNA, disrupting nucleic acid synthesis in rapidly dividing cells.
Benefits and Advantages
Used in cancer cytotoxicity research, TS‑inhibition assays and RNA/DNA synthesis modelling.
Side Effects and Risks
Myelosuppression, mucositis, cardiotoxicity and dermatologic reactions.
Datasheet
| Molecular Formula | C4H3FN2O2 |
|---|---|
| Molecular Weight | 130.08 g/mol |
| CAS Number | 51-21-8 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | 5-Fluorouracil; fluorouracil; 51-21-8; Efudex; Fluracil |
| IUPAC/Chemical Name | 5-fluoro-1H-pyrimidine-2,4-dione |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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