FLUOCINOLONE ACETONIDE
Fluocinolone acetonide is a corticosteroid reducing skin inflammation and itching. Side effects include dryness, irritation, and long‑term atrophy.
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Product Description
Mechanism of Action
Fluocinolone acetonide is a high‑potency glucocorticoid that modulates inflammatory gene expression and inhibits leukocyte migration.
Benefits and Advantages
Used in dermatologic inflammation studies, GR‑signalling assays and topical formulation development.
Side Effects and Risks
Skin thinning, adrenal suppression and pigmentation changes.
Datasheet
| Molecular Formula | C24H30O6 |
|---|---|
| Molecular Weight | 452.5 g/mol |
| CAS Number | 67-73-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | FLUOCINOLONE ACETONIDE; 67-73-2; Synalar; Fluonid; Flucinar |
| IUPAC/Chemical Name | (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one |
| InChl Key | FEBLZLNTKCEFIT-VSXGLTOVSA-N |
| InChl Code | InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1 |
| References |
3D Conformer.
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