FLUNISOLIDE HEMIHYDRATE

Flunisolide is an inhaled corticosteroid reducing airway inflammation in asthma. Side effects include oral thrush, hoarseness, and throat irritation. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 79f0779dc919 Category: Tag:

Product Description


Mechanism of Action

Flunisolide hemihydrate is an inhaled corticosteroid that binds glucocorticoid receptors to decrease airway inflammation, reduce cytokine release and improve respiratory function.

Benefits and Advantages

Used in asthma models, inhalationformulation research and airwayremodelling studies.

Side Effects and Risks

Possible oral candidiasis, hoarseness and adrenal suppression.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C24H31FO6·0.5H2O

Molecular Weight

434.5 g/mol

CAS Number

542449

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Practically insoluble

Purity

Purity information is available upon request (COA).

Synonym

flunisolide; 3385-03-3; Aerobid; Syntaris; Flunisolide anhydrous

IUPAC/Chemical Name

(1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

InChl Key

XSFJVAJPIHIPKU-XWCQMRHXSA-N

InChl Code

InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/82153;

3D Conformer.

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