FLUNARIZINE HCL
Flunarizine HCl is a calcium channel blocker used for migraine prevention. Side effects include drowsiness, weight gain, and depression. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Flunarizine HCl is a selective calciumchannel blocker with antihistaminic and antidopaminergic properties. It reduces neuronal excitability and vascular smoothmuscle tone.
Benefits and Advantages
Used in migrainepathway modelling, Ca²⁺ channel pharmacology, neurovascular research and CNS hyperexcitability studies.
Side Effects and Risks
Sedation, weight gain, depression and extrapyramidal symptoms may occur.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C26H26ClFN2·HCl |
|---|---|
| Molecular Weight | 477.4 g/mol |
| CAS Number | 30484-77-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 30484-77-6; flunarizine hydrochloride; Flunarizine HCl; Flunarizine (as hydrochloride); R 14950 |
| IUPAC/Chemical Name | 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride |
| InChl Key | RXKMOPXNWTYEHI-RDRKJGRWSA-N |
| InChl Code | InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;; |
| References |
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