FLUNARIZINE HCL

Flunarizine HCl is a calcium channel blocker used for migraine prevention. Side effects include drowsiness, weight gain, and depression.

SKU: f222415597c9 Category: Tag:

Product Description


Mechanism of Action

Flunarizine HCl is a selective calcium‑channel blocker with antihistaminic and antidopaminergic properties. It reduces neuronal excitability and vascular smooth‑muscle tone.

Benefits and Advantages

Used in migraine‑pathway modelling, Ca²⁺ channel pharmacology, neurovascular research and CNS hyperexcitability studies.

Side Effects and Risks

Sedation, weight gain, depression and extrapyramidal symptoms may occur.

Datasheet


Molecular Formula

C26H26ClFN2·HCl

Molecular Weight

477.4 g/mol

CAS Number

30484-77-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

30484-77-6; flunarizine hydrochloride; Flunarizine HCl; Flunarizine (as hydrochloride); R 14950

IUPAC/Chemical Name

1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride

InChl Key

RXKMOPXNWTYEHI-RDRKJGRWSA-N

InChl Code

InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;

References

https://pubchem.ncbi.nlm.nih.gov/compound/5282407;

3D Conformer.

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