FLUNARIZINE HCL
Flunarizine HCl is a calcium channel blocker used for migraine prevention. Side effects include drowsiness, weight gain, and depression.
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Product Description
Mechanism of Action
Flunarizine HCl is a selective calcium‑channel blocker with antihistaminic and antidopaminergic properties. It reduces neuronal excitability and vascular smooth‑muscle tone.
Benefits and Advantages
Used in migraine‑pathway modelling, Ca²⁺ channel pharmacology, neurovascular research and CNS hyperexcitability studies.
Side Effects and Risks
Sedation, weight gain, depression and extrapyramidal symptoms may occur.
Datasheet
| Molecular Formula | C26H26ClFN2·HCl |
|---|---|
| Molecular Weight | 477.4 g/mol |
| CAS Number | 30484-77-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 30484-77-6; flunarizine hydrochloride; Flunarizine HCl; Flunarizine (as hydrochloride); R 14950 |
| IUPAC/Chemical Name | 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride |
| InChl Key | RXKMOPXNWTYEHI-RDRKJGRWSA-N |
| InChl Code | InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;; |
| References |
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