FLUMETHASONE PIVALATE

Flumethasone pivalate is a potent topical steroid with antiinflammatory effects. Side effects include burning, dryness, and potential atrophy. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 0ba1ca57d2fc Category: Tag:

Product Description


Mechanism of Action

Flumethasone pivalate is an esterified glucocorticoid with enhanced lipophilicity and prolonged tissue activity. It suppresses inflammatory gene transcription and modulates immunecell responses.

Benefits and Advantages

Used in dermatologic corticosteroid research, topical formulation design and cytokinemodulation studies.

Side Effects and Risks

Possible skin thinning, systemic absorption effects and immunosuppression.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C27H36F2O5

Molecular Weight

494.6 g/mol

CAS Number

2002-29-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

1.07e-02 g/L

Purity

Purity information is available upon request (COA).

Synonym

FLUMETHASONE PIVALATE; 2002-29-1; Locorten; Flumethasone 21-pivalate; Flumetasone pivalate

IUPAC/Chemical Name

[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate

InChl Key

JWRMHDSINXPDHB-OJAGFMMFSA-N

InChl Code

InChI=1S/C27H36F2O6/c1-14-9-16-17-11-19(28)18-10-15(30)7-8-24(18,5)26(17,29)20(31)12-25(16,6)27(14,34)21(32)13-35-22(33)23(2,3)4/h7-8,10,14,16-17,19-20,31,34H,9,11-13H2,1-6H3/t14-,16+,17+,19+,20+,24+,25+,26+,27+/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/443980;

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download