About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Flumethasone pivalate is an esterified glucocorticoid with enhanced lipophilicity and prolonged tissue activity. It suppresses inflammatory gene transcription and modulates immune‑cell responses.
Benefits and Advantages
Used in dermatologic corticosteroid research, topical formulation design and cytokine‑modulation studies.
Side Effects and Risks
Possible skin thinning, systemic absorption effects and immunosuppression.
Datasheet
| Molecular Formula | C27H36F2O5 |
|---|---|
| Molecular Weight | 494.6 g/mol |
| CAS Number | 2002-29-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 1.07e-02 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | FLUMETHASONE PIVALATE; 2002-29-1; Locorten; Flumethasone 21-pivalate; Flumetasone pivalate |
| IUPAC/Chemical Name | [2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate |
| InChl Key | JWRMHDSINXPDHB-OJAGFMMFSA-N |
| InChl Code | InChI=1S/C27H36F2O6/c1-14-9-16-17-11-19(28)18-10-15(30)7-8-24(18,5)26(17,29)20(31)12-25(16,6)27(14,34)21(32)13-35-22(33)23(2,3)4/h7-8,10,14,16-17,19-20,31,34H,9,11-13H2,1-6H3/t14-,16+,17+,19+,20+,24+,25+,26+,27+/m1/s1 |
| References |
3D Conformer.
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