FLUMAZENIL

Flumazenil is a benzodiazepine antagonist reversing sedation and overdose. Side effects include seizures in dependent patients and agitation.

SKU: aff2a5952730 Category: Tag:

Product Description


Mechanism of Action

Flumazenil is a competitive antagonist at the benzodiazepine site of the GABA‑A receptor, reversing benzodiazepine‑mediated enhancement of GABAergic inhibition.

Benefits and Advantages

Used in GABA‑A receptor studies, benzodiazepine pharmacology, sedation‑reversal research and CNS excitability modelling.

Side Effects and Risks

May induce withdrawal, seizures (in chronic benzodiazepine users) and anxiety.

Datasheet


Molecular Formula

C15H14FN3O3

Molecular Weight

303.29 g/mol

CAS Number

78755-81-4

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

flumazenil; 78755-81-4; Anexate; Flumazepil; Romazicon

IUPAC/Chemical Name

ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

InChl Key

OFBIFZUFASYYRE-UHFFFAOYSA-N

InChl Code

InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3

References

https://pubchem.ncbi.nlm.nih.gov/compound/3373;

3D Conformer.

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