FLUCYTOSINE
Flucytosine is an antifungal converted to 5‑fluorouracil inside fungal cells, inhibiting DNA/RNA synthesis. Side effects include bone marrow suppression and hepatotoxicity.
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Product Description
Mechanism of Action
Flucytosine is a fluorinated pyrimidine antifungal that converts intracellularly to 5‑FU, inhibiting DNA and RNA synthesis in susceptible fungi.
Benefits and Advantages
Used in fungal nucleotide‑synthesis studies, synergistic antifungal research and RNA‑interference pathway modelling.
Side Effects and Risks
Risks include hepatotoxicity, bone‑marrow suppression and GI toxicity.
Datasheet
| Molecular Formula | C4H4FN3O |
|---|---|
| Molecular Weight | 129.09 g/mol |
| CAS Number | 2022-85-7 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 5-Fluorocytosine; flucytosine; 2022-85-7; Fluorocytosine; Ancobon |
| IUPAC/Chemical Name | 6-amino-5-fluoro-1H-pyrimidin-2-one |
| InChl Key | XRECTZIEBJDKEO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9) |
| References |
3D Conformer.
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