FLUCYTOSINE
Flucytosine is an antifungal converted to 5fluorouracil inside fungal cells, inhibiting DNA/RNA synthesis. Side effects include bone marrow suppression and hepatotoxicity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Flucytosine is a fluorinated pyrimidine antifungal that converts intracellularly to 5FU, inhibiting DNA and RNA synthesis in susceptible fungi.
Benefits and Advantages
Used in fungal nucleotidesynthesis studies, synergistic antifungal research and RNAinterference pathway modelling.
Side Effects and Risks
Risks include hepatotoxicity, bonemarrow suppression and GI toxicity.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C4H4FN3O |
|---|---|
| Molecular Weight | 129.09 g/mol |
| CAS Number | 2022-85-7 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 5-Fluorocytosine; flucytosine; 2022-85-7; Fluorocytosine; Ancobon |
| IUPAC/Chemical Name | 6-amino-5-fluoro-1H-pyrimidin-2-one |
| InChl Key | XRECTZIEBJDKEO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9) |
| References |
3D Conformer.
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