FLOMOXEFUM
Flomoxef is an oxacephem antibiotic inhibiting bacterial cell wall synthesis. Side effects include rash, diarrhea, and elevated liver enzymes.
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Product Description
Mechanism of Action
Flomoxef is an oxacephem β‑lactam antibiotic that binds penicillin‑binding proteins (PBPs), inhibiting transpeptidation of bacterial peptidoglycan. Its oxacephem core confers strong β‑lactamase stability and broad Gram‑positive/Gram‑negative activity.
Benefits and Advantages
Used in PBP‑profiling studies, β‑lactamase resistance modelling, and cell‑wall synthesis inhibition assays.
Side Effects and Risks
Potential GI upset, hypersensitivity, hepatic enzyme elevations and rare hematologic effects.
Datasheet
| Molecular Formula | C15H18F2N6O7S2 |
|---|---|
| Molecular Weight | 496.5 g/mol |
| CAS Number | 99665-00-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Flomoxef; 99665-00-6; Flomoxefum; FMOX; V9E5U5XF42 |
| IUPAC/Chemical Name | (6R,7R)-7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | UHRBTBZOWWGKMK-DOMZBBRYSA-N |
| InChl Code | InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1 |
| References |
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