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Product Description
Mechanism of Action
Ferumoxytol is an ultrasmall superparamagnetic iron oxide nanoparticle (USPIO) coated with polyglucose sorbitol carboxymethyl ether. It delivers bioavailable iron to macrophages and is also used as an MRI contrast agent due to strong T1/T2 relaxation effects.
Benefits and Advantages
Used in nanoparticle imaging, iron metabolism studies, macrophage trafficking research and contrast‑enhanced MRI.
Side Effects and Risks
Risks include hypersensitivity, hypotension, iron overload and rare anaphylaxis.
Datasheet
| Molecular Formula | Fe3O4 |
|---|---|
| Molecular Weight | 231.53 g/mol |
| CAS Number | 722492-56-0 |
| Storage Condition | Storage at 2-30 °C (35-86 °F). DO NOT FREEZE. If there are indications that the package has been exposed to freezing, DO NOT USE. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Ferumoxytol non-stoichiometric magnetite; CLH5FT6412; Feraheme; Rienso; RefChem:55199 |
| IUPAC/Chemical Name | iron(2+);bis(iron(3+));tetrakis(oxygen(2-)) |
| InChl Key | WTFXARWRTYJXII-UHFFFAOYSA-N |
| InChl Code | InChI=1S/3Fe.4O/q+2;2*+3;4*-2 |
| References |
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