FELODIPINE
Felodipine is a calcium channel blocker causing vasodilation and lowering blood pressure. Side effects include ankle swelling, headache, and flushing. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Felodipine is a dihydropyridine calciumchannel blocker that selectively inhibits Ltype Ca²⁺ channels in vascular smooth muscle, producing vasodilation with minimal effects on cardiac conduction. It reduces peripheral vascular resistance and arterial pressure.
Benefits and Advantages
Used in vasculartone modelling, calciumchannel pharmacology, hypertension research, and smoothmuscle relaxation assays.
Side Effects and Risks
Risks include flushing, headache, ankle edema, reflex tachycardia and gingival hyperplasia. Handle with Cachannel blocker precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H19Cl2NO4 |
|---|---|
| Molecular Weight | 384.2 g/mol |
| CAS Number | 72509-76-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | felodipine; 72509-76-3; Plendil; Flodil; Modip |
| IUPAC/Chemical Name | 5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
| InChl Key | RZTAMFZIAATZDJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3 |
| References |
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