FAMCICLOVIR

Famciclovir is an antiviral prodrug of penciclovir inhibiting herpesvirus replication. Side effects include headache, nausea, and fatigue. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 0782eb122e43 Category: Tag:

Product Description


Mechanism of Action

Famciclovir is the oral prodrug of penciclovir. After absorption, it is converted to penciclovirtriphosphate, which inhibits viral DNA polymerase and terminates elongation in herpesvirus replication.

Benefits and Advantages

Used in herpesvirus replication modelling, nucleosideanalog activation studies, DNApolymerase inhibition assays, and antiviraldrug SAR analysis.

Side Effects and Risks

Risks include headache, nausea, liver enzyme elevation and rare hypersensitivity. Handle with antiviralnucleoside precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C14H19N5O4

Molecular Weight

321.33 g/mol

CAS Number

104227-87-4

Storage Condition

Store Famvir at room temperature between 59 deg and 86 °F (15 deg to 30 °C).

Solubility

Solubility in water (25 °C): > 25% w/v initially; rapidly precipitates as sparingly soluble monohydrate (2-3% w/v)

Purity

Purity information is available upon request (COA).

Synonym

famciclovir; 104227-87-4; Famvir; BRL-42810; Famciclovirum

IUPAC/Chemical Name

[2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate

InChl Key

GGXKWVWZWMLJEH-UHFFFAOYSA-N

InChl Code

InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3324;

3D Conformer.

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