EVERINOMICIN
Everninomicin is an antibacterial agent inhibiting protein synthesis, active against gram‑positive bacteria. Side effects include GI upset and potential bone marrow suppression.
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Product Description
Mechanism of Action
Everninomicin is an oligosaccharide antibiotic of the orthosomycin class that binds uniquely to the 50S ribosomal subunit at a site distinct from macrolides and aminoglycosides. By obstructing the peptidyl‑transferase center and disturbing 50S–30S subunit interactions, it inhibits bacterial protein synthesis with strong activity against multidrug‑resistant gram‑positive organisms.
Benefits and Advantages
Used in ribosomal‑binding site mapping, antimicrobial resistance‑mechanism studies, orthosomycin SAR research, and protein‑translation inhibition assays.
Side Effects and Risks
Risks include bone‑marrow suppression, GI upset, hypersensitivity reactions and potential nephrotoxicity. Handle with high‑potency antibacterial precautions.
Datasheet
| Molecular Formula | C94H150Cl2N2O34 |
|---|---|
| Molecular Weight | 1830.0 g/mol |
| CAS Number | 11051-74-0 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | Evernimicin antibiotic complex |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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