About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Etretinate is a lipophilic aromatic retinoid that binds nuclear RAR/RXR receptors, altering gene transcription involved in epithelial differentiation and keratinization. It accumulates in adipose tissue with a very long biological half‑life.
Benefits and Advantages
Used in retinoid‑receptor research, keratinocyte differentiation studies, autoimmune skin‑disease modelling, and gene‑regulation assays.
Side Effects and Risks
Risks include teratogenicity, hepatotoxicity, hyperlipidemia, mucocutaneous dryness and photosensitivity. Handle with high‑potency retinoid precautions.
Datasheet
| Molecular Formula | C23H30O3 |
|---|---|
| Molecular Weight | 354.5 g/mol |
| CAS Number | 54350-48-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | etretinate; 54350-48-0; Tegison; Ethyl etrinoate; Etretinato |
| IUPAC/Chemical Name | ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate |
| InChl Key | HQMNCQVAMBCHCO-DJRRULDNSA-N |
| InChl Code | InChI=1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+ |
| References |
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