About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Etofylline is a xanthine derivative that increases intracellular cAMP via phosphodiesterase inhibition and mild adenosinereceptor antagonism. This results in bronchodilation, central nervous system stimulation and enhanced respiratory drive.
Benefits and Advantages
Used in PDEinhibition research, airwaysmoothmuscle relaxation studies, CNSstimulant modelling, and bronchodilator SAR assays.
Side Effects and Risks
Risks include tachycardia, tremor, insomnia, nausea and arrhythmias at higher exposure. Handle with xanthinederivative precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C9H12N4O3 |
|---|---|
| Molecular Weight | 224.22 g/mol |
| CAS Number | 519-37-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | >33.6 [ug/mL] (The mean of the results at pH 7.4) |
| Purity | Purity information is available upon request (COA). |
| Synonym | ETOFYLLINE; 519-37-9; 7-(2-Hydroxyethyl)theophylline; Aethophyllinum; Frekaphyllin |
| IUPAC/Chemical Name | 7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione |
| InChl Key | NWPRCRWQMGIBOT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C9H12N4O3/c1-11-7-6(8(15)12(2)9(11)16)13(3-4-14)5-10-7/h5,14H,3-4H2,1-2H3 |
| References |
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