ETOFENAMATE
Etofenamate is a topical NSAID that inhibits prostaglandin synthesis, reducing pain and inflammation in musculoskeletal disorders. Side effects include skin irritation and redness.
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Product Description
Mechanism of Action
Etofenamate is a non‑steroidal anti‑inflammatory drug (NSAID) belonging to the flufenamic‑acid family. It inhibits cyclooxygenase (COX‑1 and COX‑2), decreasing prostaglandin synthesis involved in inflammation and pain. Its lipophilic ester form penetrates skin efficiently, making it useful in topical‑delivery research.
Benefits and Advantages
Used in COX‑inhibition assays, topical NSAID‑penetration studies, inflammation‑pathway modelling, and prostaglandin‑biosynthesis research.
Side Effects and Risks
Risks include skin irritation (topical), GI effects (systemic), photosensitivity and rare hypersensitivity reactions. Handle with NSAID‑class precautions.
Datasheet
| Molecular Formula | C18H18N2O3 |
|---|---|
| Molecular Weight | 369.3 g/mol |
| CAS Number | 30544-47-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ETOFENAMATE; 30544-47-9; 2-(2-Hydroxyethoxy)ethyl 2-((3-(trifluoromethyl)phenyl)amino)benzoate; Etofenamato; Bay d 1107 |
| IUPAC/Chemical Name | 2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate |
| InChl Key | XILVEPYQJIOVNB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2 |
| References |
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