ETOFENAMATE

Etofenamate is a topical NSAID that inhibits prostaglandin synthesis, reducing pain and inflammation in musculoskeletal disorders. Side effects include skin irritation and redness.

SKU: b971c5cea161 Category: Tag:

Product Description


Mechanism of Action

Etofenamate is a non‑steroidal anti‑inflammatory drug (NSAID) belonging to the flufenamic‑acid family. It inhibits cyclooxygenase (COX‑1 and COX‑2), decreasing prostaglandin synthesis involved in inflammation and pain. Its lipophilic ester form penetrates skin efficiently, making it useful in topical‑delivery research.

Benefits and Advantages

Used in COX‑inhibition assays, topical NSAID‑penetration studies, inflammation‑pathway modelling, and prostaglandin‑biosynthesis research.

Side Effects and Risks

Risks include skin irritation (topical), GI effects (systemic), photosensitivity and rare hypersensitivity reactions. Handle with NSAID‑class precautions.

Datasheet


Molecular Formula

C18H18N2O3

Molecular Weight

369.3 g/mol

CAS Number

30544-47-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

ETOFENAMATE; 30544-47-9; 2-(2-Hydroxyethoxy)ethyl 2-((3-(trifluoromethyl)phenyl)amino)benzoate; Etofenamato; Bay d 1107

IUPAC/Chemical Name

2-(2-hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate

InChl Key

XILVEPYQJIOVNB-UHFFFAOYSA-N

InChl Code

InChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/35375;

3D Conformer.

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