About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Ethionamide is a prodrug activated by mycobacterial monooxygenase (EtaA). The activated form inhibits InhA, an enoyl‑ACP reductase required for mycolic‑acid synthesis, thereby disrupting the integrity of the mycobacterial cell wall.
Benefits and Advantages
Used in TB‑pathway research, prodrug‑activation assays, mycolic‑acid biosynthesis studies, and multidrug‑resistance modelling.
Side Effects and Risks
Risks include hepatotoxicity, GI intolerance, neurotoxicity and hypothyroidism. Handle with antimycobacterial‑thioamide precautions.
Datasheet
| Molecular Formula | C8H10N2S |
|---|---|
| Molecular Weight | 166.25 g/mol |
| CAS Number | 536-33-4 |
| Storage Condition | Ethionamide film-coated tablets should be stored in tight containers at 20-25 °C. |
| Solubility | less than 1 mg/mL at 70 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | ethionamide; 536-33-4; 2-ethylpyridine-4-carbothioamide; Trecator; Ethioniamide |
| IUPAC/Chemical Name | 2-ethylpyridine-4-carbothioamide |
| InChl Key | AEOCXXJPGCBFJA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
