ETANERCEPT
Etanercept is a TNF inhibitor reducing inflammation in autoimmune diseases. Side effects include infections, injection-site reactions, and headache. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Etanercept is a fusion protein composed of the TNF receptor p75 linked to the Fc portion of IgG1. It binds soluble TNF and TNF, preventing their interaction with cellsurface receptors and inhibiting downstream NFBmediated inflammatory signalling. This reduces cytokinedriven inflammation in autoimmunedisease models.
Benefits and Advantages
Used in TNFpathway research, autoimmuneinflammation modelling, cytokineneutralization assays, and biologicmechanism pharmacology.
Side Effects and Risks
Risks include serious infections, injectionsite reactions, malignancy risk signals, demyelinating disorders and cytopenias. Handle with biologicTNFinhibitor precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | Protein |
|---|---|
| Molecular Weight | 150000.0 g/mol |
| CAS Number | 185243-69-0 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | Ammonium metavanadate; 7803-55-6; Ammonium monovanadate; Ammonium vanadate(V); Ammonium metavanadate (NH4VO3) |
| IUPAC/Chemical Name | TNF receptorFc fusion protein |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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