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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Eszopiclone is a nonbenzodiazepine hypnotic (Zdrug) that binds selectively to the benzodiazepine site of GABAA receptors, preferentially those containing the 1 subunit. It enhances GABAmediated chloride influx, producing neuronal hyperpolarization and sedation without strong anticonvulsant or anxiolytic effects.
Benefits and Advantages
Used in sleeparchitecture research, GABAA receptor subtype pharmacology, hypnoticmechanism modelling, and CNSsedative PK/PD studies.
Side Effects and Risks
Risks include sedation, cognitive impairment, nextday drowsiness, dependence, complex sleep behaviours and bitter taste dysgeusia. Handle with controlledsubstance hypnotic precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C17H17ClN6O3 |
|---|---|
| Molecular Weight | 388.8 g/mol |
| CAS Number | 138729-47-2 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. |
| Solubility | soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | Eszopiclone; 138729-47-2; Lunesta; (S)-Zopiclone; Estorra |
| IUPAC/Chemical Name | [(7S)-6-(5-chloro-2-pyridinyl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate |
| InChl Key | GBBSUAFBMRNDJC-INIZCTEOSA-N |
| InChl Code | InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1 |
| References |
3D Conformer.
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