ESTRADIOL BENZOATE
Estradiol benzoate is a long‑acting estrogen ester used in hormonal therapy. Side effects include nausea, breast tenderness, and clotting risk.
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Product Description
Mechanism of Action
Estradiol benzoate is an esterified form of estradiol that undergoes slow hydrolysis, providing prolonged estrogenic activity. It binds ERα/ERβ after conversion to free estradiol and influences reproductive and metabolic pathways.
Benefits and Advantages
Used in sustained‑release estrogen research, endocrine pharmacokinetics modelling, receptor‑activation assays, and reproductive‑biology applications.
Side Effects and Risks
Risks include thrombotic risk, mood changes, breast tenderness and nausea. Handle with estrogen‑ester precautions.
Datasheet
| Molecular Formula | C25H28O3 |
|---|---|
| Molecular Weight | 376.5 g/mol |
| CAS Number | 50-50-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | estradiol benzoate; 50-50-0; Estradiol 3-benzoate; Oestradiol benzoate; Oestradiol 3-benzoate |
| IUPAC/Chemical Name | [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate |
| InChl Key | UYIFTLBWAOGQBI-BZDYCCQFSA-N |
| InChl Code | InChI=1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1 |
| References |
3D Conformer.
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