ERYTHROMYCIN ETHYL SUCCINATE
Erythromycin lauryl sulfate is an antimicrobial salt form used topically. Side effects include skin dryness, irritation, and peeling. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
This acidresistant ester of erythromycin improves stability in gastric acid and ensures effective delivery of active drug to systemic circulation. Mechanism remains inhibition of the 50S ribosomal subunit.
Benefits and Advantages
Used in PK/PD macrolide modelling, esterstability studies, pediatric antimicrobial testing, and bacterialprotein synthesis inhibition research.
Side Effects and Risks
Risks include GI upset, mild hepatotoxicity and druginteraction potential. Handle with erythromycinester precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C43H75NO16 |
|---|---|
| Molecular Weight | 862.1 g/mol |
| CAS Number | 1264-62-6 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. |
| Solubility | FREELY SOL IN ACETONE & CHLOROFORM; SOL IN 95% ETHANOL & BENZENE; SPARINGLY SOL IN ETHER; VERY SLIGHTLY SOL IN WATER |
| Purity | Purity information is available upon request (COA). |
| Synonym | erythromycin ethylsuccinate; 1264-62-6; Erythromycin ethyl succinate; Erythrocin ethyl succinate; anamycin |
| IUPAC/Chemical Name | 4-O-[(2S,3R,4S,6R)-4-(dimethylamino)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl] 1-O-ethyl butanedioate |
| InChl Key | NSYZCCDSJNWWJL-YXOIYICCSA-N |
| InChl Code | InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,32+,34+,35-,36-,37+,38-,40+,41-,42-,43-/m1/s1 |
| References |
3D Conformer.
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