ERGOCRISTINE ACETONATE

Ergocristine acetonate is an ergot alkaloid modulating dopamine and serotonin receptors, used in vascular and hormonal disorders. Side effects include nausea, vasospasm, and headache. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 22e4886a8495 Category: Tag:

Product Description


Mechanism of Action

Ergocristine acetonate is an ergot alkaloid derivative that acts as a partial agonist/antagonist at multiple serotonin (5HT), dopamine (D) and adrenergic () receptors. It modulates vascular tone and central neurotransmission, and historically has been part of ergotbased mixtures used in cerebrovascular and cognitive research.

Benefits and Advantages

Used in ergotalkaloid receptorbinding studies, cerebrovasculartone modelling, 5HT/DA/receptor pharmacology, and mixedagonist/antagonist SAR investigations.

Side Effects and Risks

Risks include vasospasm, hypertension or hypotension, nausea, paresthesias and, with chronic high exposure, ergotism (ischemia, fibrosis). Handle with ergotalkaloid precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C35H41N5O6·C3H6O

Molecular Weight

609.7 g/mol

CAS Number

8060-66-2

Storage Condition

Store in a cool, dry place; protect from light

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

IUPAC/Chemical Name

Methyl (5€²Î±)-12€²-hydroxy-2€²-methyl-5€²-(prop-1-en-2-yl)ergoline-8-carboxylate

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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