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Product Description
Mechanism of Action
Ergocristine acetonate is an ergot alkaloid derivative that acts as a partial agonist/antagonist at multiple serotonin (5‑HT), dopamine (D₂) and adrenergic (α) receptors. It modulates vascular tone and central neurotransmission, and historically has been part of ergot‑based mixtures used in cerebrovascular and cognitive research.
Benefits and Advantages
Used in ergot‑alkaloid receptor‑binding studies, cerebrovascular‑tone modelling, 5‑HT/DA/α‑receptor pharmacology, and mixed‑agonist/antagonist SAR investigations.
Side Effects and Risks
Risks include vasospasm, hypertension or hypotension, nausea, paresthesias and, with chronic high exposure, ergotism (ischemia, fibrosis). Handle with ergot‑alkaloid precautions.
Datasheet
| Molecular Formula | C35H41N5O6·C3H6O |
|---|---|
| Molecular Weight | 609.7 g/mol |
| CAS Number | 8060-66-2 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | Methyl (5²Î±)-12²-hydroxy-2²-methyl-5²-(prop-1-en-2-yl)ergoline-8-carboxylate |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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