ENOXACINE
Enoxacine is a fluoroquinolone effective against gram-negative bacteria. Side effects include dizziness, nausea, and photosensitivity.
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Product Description
Mechanism of Action
Enoxacine is a fluoroquinolone that inhibits bacterial DNA gyrase (GyrA/GyrB) and topoisomerase IV, preventing DNA replication and segregation. It exhibits strong gram‑negative activity and good intracellular penetration.
Benefits and Advantages
Used in DNA‑replication inhibition studies, topoisomerase‑interaction assays, bacterial‑kinetics research, and resistance‑mutation profiling.
Side Effects and Risks
Risks include tendon rupture, neuropathy, CNS overstimulation, hepatotoxicity and QT prolongation. Handle with quinolone‑class precautions.
Datasheet
| Molecular Formula | C15H17FN2O3 |
|---|---|
| Molecular Weight | 320.32 g/mol |
| CAS Number | 74011-58-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | enoxacin; 74011-58-8; Penetrex; Enoxacine; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid |
| IUPAC/Chemical Name | 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid |
| InChl Key | IDYZIJYBMGIQMJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23) |
| References |
3D Conformer.
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