About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Endrisone (Δ¹‑cortienic acid derivatives) is a topical corticosteroid that binds glucocorticoid receptors, suppressing pro‑inflammatory cytokines, inhibiting leukocyte migration and reducing erythema and edema. It has moderate potency with good epidermal penetration.
Benefits and Advantages
Used in dermal‑inflammation research, GR‑signalling assays, cytokine‑suppression modelling, and dermatologic‑pharmacology studies.
Side Effects and Risks
Risks include skin atrophy, irritation, HPA‑axis suppression (rare), telangiectasia and allergic reactions. Handle with corticosteroid precautions.
Datasheet
| Molecular Formula | C24H32O4 |
|---|---|
| Molecular Weight | 342.5 g/mol |
| CAS Number | 35100-44-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Endrisone; ENDRYSONE; Endrisona; 35100-44-8; Endrysone [USAN] |
| IUPAC/Chemical Name | (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one |
| InChl Key | VDNZZIYSCXESNI-ILSZZQPISA-N |
| InChl Code | InChI=1S/C22H30O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h7-8,10,12,15-17,19-20,25H,5-6,9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1 |
| References |
3D Conformer.
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